Clinical evaluation of platelet concentrates stored for one to five days

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Clinical evaluation of platelet concentrates stored for one to five days.

There are no large-scale data available describing the increments obtained with platelet concentrates stored for varying durations. Platelet concentrates prepared by standard techniques were stored at 22 degrees C with horizontal agitation in PL-732 bags and administered to clinically stable, nonalloimmunized recipients known to respond well to random donor platelet transfusions. The platelet c...

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Evaluation of platelet storage lesions in platelet concentrates stored for seven days.

BACKGROUND & OBJECTIVES Platelet storage lesions (PSL) are detrimental to the post transfusion functional capacity of platelets. As EDTA enhances the storage-induced changes, changes in platelet indices with and without EDTA incubation are promising new tests to monitor the PSL. The present study was undertaken to monitor the PSL in 40 units of pooled platelet concentrates harvested by platelet...

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Evaluation of Biochemical Parameters of Platelet Concentrates Stored in Plasma or in A Platelet Additive Solution (Composol)

Abstract Objective Removing plasma from the platelet concentrate (PC) medium could be an effective way to increase the safety of this product. The goal of this study was to compare PC stored in plasma or in an additive solution (Composol) with in vitro testing. Materials and Methods Fifty-four single donor PCs were prepared from Iranian Blood Transfusion Organization (IBTO). Each PC unit wa...

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Bacterial contamination of platelet concentrates stored at 20 ° C

In a series of important studies Murphy and his colleagues demonstrated that the preparation and storage of platelet-rich plasma and platelet concentrates at 22°C rather than 4°C improved their life span in vivo (Murphy and Gardner, 1969; Murphy, Sayar, and Gardner, 1970). The potential clinical relevance of this finding has been confirmed by Handin and Valeri (1971), and it is likely that this...

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Lipid composition of freshly prepared and stored platelet concentrates.

To evaluate the possibility that changes in lipid composition might be related to the functional lesion that develops when platelets are stored as concentrates for several days, we measured lipid constituents of platelets in freshly prepared concentrates and in concentrates stored for 72 hr at 4 degrees C or at 20 degrees C under standard blood banking conditions. At 20 degrees C, but not at 4 ...

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ژورنال

عنوان ژورنال: Blood

سال: 1986

ISSN: 0006-4971,1528-0020

DOI: 10.1182/blood.v67.6.1591.1591